Objective: The purpose of this study was to assess the microparticles serum levels as a predictor of maternal and fetal complications in preeclampsia.

Materials and methods: In this cross sectional study, 50 pregnant women with preeclampsia (mild preeclampsia [n=29] and severe preeclampsia [n=21]) and 50 normotensive matched control group were recruited. Maternal blood endothelial microparticles (EMP), platelet microparticles (PMP), hemoglobin, hematocrit, platelet count, liver enzymes, and total bilirubin levels were assessed in all patients.

Results: EMP count was significantly higher in preeclampsia group compared with controls. Moreover, significantly higher EMP levels were observed in patients with severe preeclamp-sia compared with mild preeclampsia. There was a significant negative correlation between platelet count and EMP. Also, EMP was correlated positively with AST and bilirubin levels. EMP levels was significantly higher in cases with neonatal death (p=0.04). No significant correlation was observed between PMP and EMP levels.

Conclusion: EMP levels tend to be increased with severity of preeclampsia. Moreover, higher EMP levels are seen in cases with fetal death.